In vivo molecular imaging of [125I]-labeled 3-iodothyronamine: A hibernation-inducing agent

► A SPECT/CT imaging of [125I]-T1AM has been performed in a mouse. ► A radiochemical yield of [125I]-T1AM was 40%, and the radiochemical purity was >99%. ► T1AM was also synthesized to compare with [125I]-T1AM.