Ginkgo biloba extract alters the binding of the sodium [123I] iodide (Na123I) on blood constituents

We evaluated the in vitro effect of an aqueous extract of Ginkgo biloba (EGb) on the distribution in blood cells (BC) and plasma (P) and on the binding of Na123I to the blood constituents using precipitation with trichloroacetic acid. The radioactivity percentages insoluble (SF) and insoluble fraction (IF) of blood constituents were determined. The EGb interfered (p<0.05) on the distribution of Na123I in the P (from 69.64 to 86.13) and BC (from 30.36 to 13.87) and altered the fixation of the Na123I in IF-P and in IF-BC.

► Interaction between the Ginkgo biloba and blood constituents radiolabeled.
► Modification of the binding of sodium iodide (Na123I) to the blood constituents.
► This alteration should have influence in a diagnosis of nuclear medicine.