کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
1879739 | 1042591 | 2007 | 6 صفحه PDF | دانلود رایگان |
عنوان انگلیسی مقاله ISI
55Cobalt complexes with pendant carbohydrates as potential PET imaging agents
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موضوعات مرتبط
مهندسی و علوم پایه
فیزیک و نجوم
تشعشع
پیش نمایش صفحه اول مقاله
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چکیده انگلیسی
Bis-ligand cobalt(II) complexes of four 3-hydroxy-4-pyridinone ligands with pendant carbohydrates were synthesized and examined for their potential as radiopharmaceuticals. Non-radioactive complexes were prepared on the macroscopic scale and characterized by elemental analysis, mass spectrometry, IR and UV/visible spectroscopy. Facile radiolabeling produced the 55Co complexes in high radiochemical yields (>95%). Identification of the radiolabeled compounds was accomplished by HPLC comparison with the corresponding non-radioactive complexes.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Applied Radiation and Isotopes - Volume 65, Issue 12, December 2007, Pages 1303–1308
Journal: Applied Radiation and Isotopes - Volume 65, Issue 12, December 2007, Pages 1303–1308
نویسندگان
Cara L. Ferreira, Suzanne Lapi, Jennifer Steele, David E. Green, Thomas J. Ruth, Michael J. Adam, Chris Orvig,