Synchrotron X-ray powder diffraction data of LASSBio-1515: A new N-acylhydrazone derivative compound

In this work, synchrotron X-ray powder diffraction data allowed for a successful indexing of LASSBio-1515 compound, candidate to analgesic and anti-inflammatory activity. X-ray powder diffraction data collected in transmission and high-throughput geometries were used to analyze this compound. The X-ray wavelength of the synchrotron radiation used in this study was determined to be λ=1.55054 Å. LASSBio-1515 was found to be monoclinic with space group P21/c and unit cell parameters a=11.26255(16) Å, b=12.59785(16) Å, c=8.8540(1) Å, β=90.5972(7)° and V=1256.17(3) Å3.

► LASSBio-1515 is a new N-acylhydrozone derivative compound.
► Molecular simplification strategy used in the rational planning of LASSBio-1515.
► Synchrotron XRPD data allowed for a successful indexing of LASSBio-1515 compound.
► This was indexed as having a monoclinic system (P21/c).