کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
1912198 1400161 2016 12 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Understanding cognition in older patients with cancer
ترجمه فارسی عنوان
فهم شناخت در بیماران مسن مبتلا به سرطان
موضوعات مرتبط
علوم زیستی و بیوفناوری بیوشیمی، ژنتیک و زیست شناسی مولکولی سالمندی
چکیده انگلیسی

Cancer and neurocognitive disorders, such as dementia and delirium, are common and serious diseases in the elderly that are accompanied by high degree of morbidity and mortality. Furthermore, evidence supports the under-diagnosis of both dementia and delirium in older adults. Complex questions exist regarding the interaction of dementia and delirium with cancer, beginning with guidelines on how best measure disease severity, the optimal screening test for either disorder, the appropriate level of intervention in the setting of abnormal findings, and strategies aimed at preventing the development or progression of either process. Ethical concerns emerge in the research setting, pertaining to the detection of cognitive dysfunction in participants, validity of consent, disclosure of abnormal results if screening is pursued, and recommended level of intervention by investigators. Furthermore, understanding the ways in which comorbid cognitive dysfunction and cancer impact both cancer and non-cancer-related outcomes is essential in guiding treatment decisions. In the following article, we will discuss what is presently known of the interactions of pre-existing cognitive impairment and delirium with cancer. We will also discuss identified deficits in our knowledge base, and propose ways in which innovative research may address these gaps.

ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Journal of Geriatric Oncology - Volume 7, Issue 4, July 2016, Pages 258–269
نویسندگان
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