کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
1912601 1047182 2014 8 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Feasibility and promise of a 6-week program to encourage physical activity and reduce joint symptoms among elderly breast cancer survivors on aromatase inhibitor therapy
ترجمه فارسی عنوان
امکان سنجی و وعده یک برنامه 6 هفته ای برای تشویق فعالیت بدنی و کاهش علائم مشترک در بازماندگان سرطان سینه سالمند در درمان مهار کننده آروماتاز
کلمات کلیدی
موضوعات مرتبط
علوم زیستی و بیوفناوری بیوشیمی، ژنتیک و زیست شناسی مولکولی سالمندی
چکیده انگلیسی

BackgroundNational guidelines suggest that women with hormone receptor positive breast cancer be considered for adjuvant endocrine treatment with an aromatase inhibitor (AI). Joint symptoms (arthralgia) are a common AI side-effect. There is a need for effective approaches to arthralgia management that enable survivors to remain on AI therapy while optimizing as pain-free a life as possible. This feasibility study investigates a 6-week self-directed walking program in a sample of elderly female breast cancer survivors on AIs reporting joint pain.MethodsIntervention: Walk With Ease (WWE) goal—minimum 30 min of walking 5 days a week (150 min per week). Eligibility: age > 65; Stage I–III breast cancer; ≥ 3 months of AI therapy; self-reported joint pain/stiffness. Measures: (1) walking—number of days/week and number of minutes/walk, (2) visual analog scales (VAS) for joint pain, fatigue and stiffness, and (3) arthritis self-efficacy (ASE) to manage joint pain and fatigue. Statistics: t-tests, correlation coefficients and effect sizes.ResultsSample target of 20 was achieved—mean age 71 (65–87), 85% Caucasian, mean BMI 29. Proportion walking 150 min/week increased from 21% at baseline to 50% at 6 weeks (p < 0.001). Mean joint pain at baseline (39.7 + 26.9) decreased 10% (p = 0.63), fatigue (37.4 + 33.3) decreased 19% (p = 0.31), joint stiffness (46.1 + 27.2) decreased 32% (p = 0.07).ConclusionsA self-directed walking program among elderly breast cancer survivors on AI therapy significantly increased total time of walking per week over a 6 week period. Joint pain, stiffness, and fatigue also decreased, although not significantly. Testing within a larger sample is warranted.

ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Journal of Geriatric Oncology - Volume 5, Issue 2, April 2014, Pages 148–155
نویسندگان
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