کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
1916905 1535219 2006 4 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Heredity in multiple system atrophy
موضوعات مرتبط
علوم زیستی و بیوفناوری بیوشیمی، ژنتیک و زیست شناسی مولکولی سالمندی
پیش نمایش صفحه اول مقاله
Heredity in multiple system atrophy
چکیده انگلیسی

We investigated the family histories of 157 Japanese patients with probable or possible multiple system atrophy (MSA). A family history of neurodegenerative disorders was only detected in three MSA patients (1.9%). We evaluated these patients by careful neurological examination, neuroimaging studies, and genetic studies to exclude hereditary spinocerebellar ataxia with a similar clinical phenotype to MSA. The results indicated that one of them had a family history of MSA. Although the familial presence of neurodegenerative disorders is rare in MSA patients, the existence of such cases suggests that MSA may have a genetic background.

ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Journal of the Neurological Sciences - Volume 240, Issues 1–2, 15 January 2006, Pages 107–110
نویسندگان
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