کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
1922847 1535842 2016 7 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Detecting presence of cardiovascular disease through mitochondria respiration as depicted through biophotonic emission
ترجمه فارسی عنوان
تشخیص حضور بیماری های قلبی عروقی از طریق تنفس میتوكندری كه از طریق انتشار بیوفوتونیك نشان داده می شود
کلمات کلیدی
میتوکندریا؛ بیماری قلب و عروقی؛ بیوفوتونها؛ استرس اکسیداتیو واکنش پذیر (ROS)؛ سیستم Clearview
موضوعات مرتبط
علوم زیستی و بیوفناوری بیوشیمی، ژنتیک و زیست شناسی مولکولی سالمندی
چکیده انگلیسی


• Detecting components of cardiovascular disease through biophoton emission.
• Non-invasive way of measuring in-vivo cell to cell communication.
• Electrophysiological tool detects presence or absence of cardiovascular disease.

AimsIncreased production of reactive oxygen species (ROS) in mitochondria, play an important role in the cardiovascular system. Furthermore, oxidative metabolism of mitochondria comprised of biophoton emissions, are linked to ROS and oxidative stress. In this review we investigated the association between the ability of ClearViewTM system (ClearView) to indicate the presence or absence of cardiovascular disease through mitochondria respiration as depicted through biophotonic emission.Methods and resultsOne hundred and ninety-five out of the three hundred and fifty-three human subjects enrolled in this prospective, single site study had at least one cardiovascular related diagnosis. Measurements with ClearView consisted of scanning all 10 fingers twice. Images were captured through the ClearView software and analyzed to produce a scale that indicates the presence or absence of cardiovascular disease. The association of ClearView's ability to indicate the presence or absence of cardiovascular disease with a physician's diagnosis was assessed using odds ratios (OR) and area under ROC curve (AUC). Adjusting for age, OR of ClearView measurements conducted with capacitive barrier was 3.44 (95%CI: 2.13, 5.55) and the OR without the capacitive barrier was 2.15 (95%CI: 1.42, 3.23). The OR in men were 5.91 (95%CI: 2.35, 14.85) and 2.88 (95%CI: 1.38, 6.01), adjusting for age and corresponding to with and without capacitive barrier. The OR in women were 3.50 (95%CI: 1.86, 6.59) and 2.09 (95%CI: 1.20, 3.64) with and without capacitive barrier. AUCs for measurements with capacitive barrier were >0.90.ConclusionClearView detected the presence or absence of cardiovascular disease independent of other conditions.

Figure optionsDownload as PowerPoint slide

ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Redox Biology - Volume 8, August 2016, Pages 11–17
نویسندگان
, , ,