کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
1923438 | 1048895 | 2013 | 5 صفحه PDF | دانلود رایگان |
عنوان انگلیسی مقاله ISI
Identification and location of the cocaine and amphetamine regulated transcript (CART) in the abomasum of cattle
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کلمات کلیدی
DABCARTLIMDNES3,3′-diaminobenzidine - 3،3'-diaminobenzidineAbomasum - آبوموشImmunoreactivity - ایمنی فعالImmunohistochemistry - ایمونوهیستوشیمیCNS - دستگاه عصبی مرکزیcentral nervous system - سیستم عصبی مرکزیdiffuse neuroendocrine system - سیستم نوروآنتیوکرین منتشرneuroendocrine - عصبی عضلانیlike immunoreactivity - مانند ایمنی فعالcocaine and amphetamine regulated transcript - کوکائین و رونویسی تنظیم شده توسط آمفتامینCattle - گاو
موضوعات مرتبط
علوم زیستی و بیوفناوری
بیوشیمی، ژنتیک و زیست شناسی مولکولی
زیست شیمی
پیش نمایش صفحه اول مقاله
چکیده انگلیسی
The cocaine and amphetamine regulated transcript (CART) belongs to the group of peptides with anorexigenic properties and is present in many areas of the central and peripheral nervous systems of numerous mammalian species. Research has suggested an effect on the feeling of appetite and satiety; however, there are no clear clues as to the role of CART in specific organs, including the stomach. Considering the specificity of cattle feeding and digestion, CART may play a highly significant role possibly associated with the option of administering greater amounts of high-volume feeds. Based on the results of immunohistochemical staining of abomasum samples prepared from hybrid bulls, the presence of CART-positive structures and CART distribution were determined in the mucosa, submucosa and muscularis layers of the stomach. Abundant sites of CART were found in the myenteric plexus, nerve fibers innervating the myocytes of the myenteron, neuroendocrine cells of the diffuse neuroendocrine system and the submucous plexus. The preliminary stage of abomasal CART detection suggests that CART is an agent that strongly affects the regulation of motor activity involved in stomach emptying and in secretory functions of the stomach. However, further research is necessary to explain the relationship.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Acta Histochemica - Volume 115, Issue 4, May 2013, Pages 371-375
Journal: Acta Histochemica - Volume 115, Issue 4, May 2013, Pages 371-375
نویسندگان
Izabela Janiuk, Krzysztof MÅynek, JarosÅaw Wysocki,