Low density lipoprotein S-homocysteinylation is increased in acute myocardial infarction patients

ObjectivesWe have investigated on the levels of homocysteine linked to LDL in acute myocardial infarction patients.Design and methodsWe used capillary electrophoresis to measure LDL-bound thiols in 16 AMI individuals and 32 healthy volunteers.ResultsWe found a significant increase of apo-B homocysteine and cysteine levels in LDL fraction of AMI subjects.ConclusionsOur findings suggest that also LDL S-homocysteinylation may be considered among the markers for the CVD risk evaluation.