کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
1970236 1538916 2007 4 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Mutual interference between serum thyroglobulin and antithyroglobulin antibody in an automated chemiluminescent immunoassay
موضوعات مرتبط
علوم زیستی و بیوفناوری بیوشیمی، ژنتیک و زیست شناسی مولکولی زیست شیمی
پیش نمایش صفحه اول مقاله
Mutual interference between serum thyroglobulin and antithyroglobulin antibody in an automated chemiluminescent immunoassay
چکیده انگلیسی

Objectives:To investigate the analytical interference between serum Tg and TgAb.Design and methods:Tg and TgAb were measured on an automated chemiluminescent immunoassay system in mixed sera from DTC patients and individual samples spiked with exogenous Tg.Results:Tg and TgAb recoveries in mixed patient samples were inversely correlated with expected TgAb or Tg concentrations, respectively. Impaired TgAb recoveries were also found in 50% (10/20) samples with high Tg in the exogenous recovery tests.Conclusions:Mutual but not equal analytical interference between Tg and TgAb is present and concentration-dependent with interpatient variability.

ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Clinical Biochemistry - Volume 40, Issues 9–10, June 2007, Pages 735–738
نویسندگان
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