Transcutaneous bilirubin measurement: Comparison of Respironics BiliCheck and JM-103 in a normal newborn population

ObjectivesTo compare the accuracy of BiliCheck™ (Respironics, Marietta, GA) and Konica-Minolta Air Shield JM-103 (Drager Medical Inc, Telford, PA) to evaluate total serum bilirubin (TSB).MethodsProspective blinded study comparing two diagnostic devices in 630 neonates requiring TSB measurement.ResultsLinear regression analysis showed a good correlation between BiliCheck™ and TSB (r = 0.8212) as well as between JM-103 and TSB (r = 0.8686). BiliCheck shows a tendency to underestimate TSB. The mean difference in TSB–TcB was − 1.4 mg/dL for BC (− 4.7/+ 1.8 mg/dL) and 0.3 mg/dL for JM-103 (− 2.6/+ 3.2 mg/dL). ROC analysis for TSB ≥ 12 mg/dL showed area under the curve for BiliCheck™ significantly lower than those for JM-103 (p < 0.0001). JM-103 resulted less time expensive than BiliCheck.ConclusionsIn spite of similar diagnostic accuracy JM-103 could be preferred for some practical advantages, but its suitability in performing universal screening for severe hyperbilirubinemia deserves further investigations.

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