کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
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1971005 | 1538903 | 2009 | 7 صفحه PDF | دانلود رایگان |
ObjectiveThis purpose of this study was to determine if serum procalcitonin (PCT) concentration at the time of admission to the ICU is a predictor of all-cause short-term mortality.Design and methodsThis prospective cross-sectional study was conducted over a 16-month period with 86 consecutive critically ill patients. The semi-quantitative PCT-Q test was performed and APACHE II scores and C-reactive protein (CRP) concentrations were determined within 24 h of admission.ResultsPCT-Q test value was a better predictor of all-cause short-term mortality than CRP value or APACHE II score. PCT ≥ 10 ng/mL was highly and independently correlated with mortality. Use of PCT-Q ≥ 10 ng/mL was superior to use of APACHE II ≥ 25 or CRP ≥ 10 mg/dL as a predictor of poor outcome.ConclusionsA PCT-Q value ≥ 10 ng/mL obtained at the time of admission to the ICU is a strong predictor of short-term mortality.
Journal: Clinical Biochemistry - Volume 42, Issues 10–11, July 2009, Pages 1025–1031