کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
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1971539 | 1538915 | 2007 | 6 صفحه PDF | دانلود رایگان |
Objectives:The purpose of this study was to determine serum prolidase activity in patients with hypertension and its relation with left ventricular hypertrophy.Design and methods:Serum prolidase activity was measured spectrophotometrically in hypertensive patients with (Group II, n = 30) and without left ventricular hypertrophy (Group III, n = 30) and in control group (Group I, n = 30).Results:Prolidase activity was significantly lower in Group I than in Groups II and III (44.64 ± 6.42 U/L vs. 54.14 ± 6.30 U/L and 54.25 ± 7.14 U/L, respectively; ANOVA, p < 0.001). We revealed significant correlation between prolidase activity and presence and duration of hypertension (both of p < 0.05) but not left ventricular mass index. Multivariate analysis shown that prolidase activity was significantly associated with age (β = 0.481, p < 0.001) and duration of hypertension (β = 0.396, p < 0.001).Conclusions:Our data show that serum prolidase activity is associated with the presence hypertension independent of left ventricular hypertrophy.
Journal: Clinical Biochemistry - Volume 40, Issues 13–14, September 2007, Pages 1020–1025