کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
1974155 | 1060341 | 2007 | 6 صفحه PDF | دانلود رایگان |
عنوان انگلیسی مقاله ISI
Characterization of the hemoglobins of the adult brushtailed possum, Trichosurus vulpecula (Kerr) reveals non-genetic heterogeneity
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موضوعات مرتبط
علوم زیستی و بیوفناوری
بیوشیمی، ژنتیک و زیست شناسی مولکولی
زیست شیمی
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چکیده انگلیسی
The hemoglobins contained within the red blood cells of the adult brushtail possum exhibited cooperative (n = 2.6) oxygen binding curves with an associated p50 of 38 mm Hg at pH 7.4 and a large Bohr effect (− 0.60). Stripped hemolysate showed a Bohr effect of − 0.27, and was sensitive to added DPG (K = 56 μmol L− 1), ATP (K = 130 μmol L− 1), and chloride ions. Four isoforms of hemoglobin were identified using isoelectric focusing. Mass spectrometry indicated that all four isoforms most likely represent the same gene products which have differentially undergone post-translational deamidation and glutathionylation. The oxygen binding characteristics of three isolated isohemoglobins have been determined.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Comparative Biochemistry and Physiology Part A: Molecular & Integrative Physiology - Volume 148, Issue 3, November 2007, Pages 498–503
Journal: Comparative Biochemistry and Physiology Part A: Molecular & Integrative Physiology - Volume 148, Issue 3, November 2007, Pages 498–503
نویسندگان
Kristen Henty, Rufus M.G. Wells, Thomas Brittain,