کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
1985662 1540229 2016 10 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Antioxidant and hepatoprotective activities of intracellular polysaccharide from Pleurotus eryngii SI-04
موضوعات مرتبط
علوم زیستی و بیوفناوری بیوشیمی، ژنتیک و زیست شناسی مولکولی زیست شیمی
پیش نمایش صفحه اول مقاله
Antioxidant and hepatoprotective activities of intracellular polysaccharide from Pleurotus eryngii SI-04
چکیده انگلیسی


• Two major fractions (IPS-1 and IPS-2) of IPS were obtained.
• Characterizations of IPS and its fractions were processed.
• IPS-2 was an acidic polysaccharide with antioxidant and hepatoprotective effects.
• Findings indicated that IPS-2 had potential effects in functional foods.

In present study, the intracellular polysaccharide (IPS) and its two fractions of IPS-1 and IPS-2 were obtained and purified by DEAE-52 cellulose chromatography from Pleurotus eryngii SI-04 mycelia, and their hepatoprotective effects were also investigated. The results showed that the IPS-2 had superior hepatoprotective effects by increasing the serum enzyme activities and bilirubin (BIL) levels, decreasing the serum albumin (ALB) and triglyceride (TG) levels, improving the hepatic antioxidant status, and ameliorating the hepatic structure damage. Furthermore, the monosaccharide composition and main bond types were also analyzed. These conclusions demonstrated that the both IPS and its fractions might be suitable for functional foods and natural drugs in preventing the acute liver damage.

ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: International Journal of Biological Macromolecules - Volume 91, October 2016, Pages 568–577
نویسندگان
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