کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
1985794 | 1540235 | 2016 | 6 صفحه PDF | دانلود رایگان |
• The present work deals with the cyclization of o-substituted chalcones to respective flavanones in presence of BSA in aqueous medium in absence of any other reagent.
• The results are deduced on the 1H NMR spectral data.
• The work can be beneficial in correlating the biological properties of chalcones and flavanones.
The emergence of albumin as a biocatalyst has created continuous interest of researchers for its application not only in the field of asymmetric oxidations and reductions but also in chemical reactions such as additions, condensations and eliminations. In the present work we report the cyclization reactions in presence of an albumin protein, Bovine Serum Albumin (BSA). The work is focused on cyclization of 2′-hydroxychalcone and 2′-aminochalcone to flavanones and azaflavanone, respectively. The results are supported by 1H NMR studies.
Journal: International Journal of Biological Macromolecules - Volume 85, April 2016, Pages 23–28