کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
1987283 | 1540287 | 2011 | 6 صفحه PDF | دانلود رایگان |
عنوان انگلیسی مقاله ISI
Isolation and characterization of novel protein with anti-fungal and anti-inflammatory properties from Aloe vera leaf gel
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کلمات کلیدی
موضوعات مرتبط
علوم زیستی و بیوفناوری
بیوشیمی، ژنتیک و زیست شناسی مولکولی
زیست شیمی
پیش نمایش صفحه اول مقاله
![عکس صفحه اول مقاله: Isolation and characterization of novel protein with anti-fungal and anti-inflammatory properties from Aloe vera leaf gel Isolation and characterization of novel protein with anti-fungal and anti-inflammatory properties from Aloe vera leaf gel](/preview/png/1987283.png)
چکیده انگلیسی
The Aloe protein of 14 kDa from the Aloe vera leaf gel was isolated by an ion exchange chromatography using DEAE-cellulose and CM-cellulose column. The purified Aloe protein exhibited a potent anti-fungal activity against Candida paraprilosis, Candida krusei and Candida albicans. In addition, the purified Aloe protein also showed an anti-inflammatory property against pure lipoxygenase and cyclooxygenase-2 with 84% and 73% inhibition, respectively, and was verified by binding with these proteins by real time method by the phenomenon of surface plasmon resonance. This Aloe protein is a novel protein possessing antifungal and anti-inflammatory properties and thus sets a platform to be used as a medicinal plant product.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: International Journal of Biological Macromolecules - Volume 48, Issue 1, 1 January 2011, Pages 38–43
Journal: International Journal of Biological Macromolecules - Volume 48, Issue 1, 1 January 2011, Pages 38–43
نویسندگان
Swagata Das, Biswajit Mishra, Kamaldeep Gill, Md. Saquib Ashraf, Abhay Kumar Singh, Mou Sinha, Sujata Sharma, Immaculata Xess, Krishna Dalal, Tej Pal Singh, Sharmistha Dey,