کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
1987536 1540289 2010 6 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Theory of crystallization of a closed macromolecule
کلمات کلیدی
موضوعات مرتبط
علوم زیستی و بیوفناوری بیوشیمی، ژنتیک و زیست شناسی مولکولی زیست شیمی
پیش نمایش صفحه اول مقاله
Theory of crystallization of a closed macromolecule
چکیده انگلیسی

In this paper we propose a theory, which considers the behavior of a circular macromolecule nearing its transition phase to a condensed state. In particular, the explicit dependence of the phase transition characteristics on the macromolecule's topology is discussed. An important example of a circular macromolecule is bacterial DNA, and although the crystalline state appears incompatible with life, simple organisms use crystallization of DNA for protection against varied environmental assaults. It is shown that the cellular conditions that determine super-helical properties regulate the packaging of DNA as well and, therefore, regulate bacterial endurance and virulence.

ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: International Journal of Biological Macromolecules - Volume 47, Issue 4, 1 November 2010, Pages 439–444
نویسندگان
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