Neuregulin-1β regulates outgrowth of neurites and migration of neurofilament 200 neurons from dorsal root ganglial explants in vitro

► Organotypic rat dorsal root ganglion explant culture model was established. ► Effects of neuregulin-1β on neurite outgrowth and neuronal migration were evaluated. ► Neuregulin-1β promotes neurite outgrowth of the explant. ► Neuregulin-1β promotes neuronal migration from the explant.