Biochemical, physiological and morfological responses in common carp (Cyprinus carpio L.) after long-term exposure to terbutryn in real environmental concentration

The effects of terbutryn at concentrations of 0.02 (reported concentration in Czech rivers), 0.2, and 2.0 μg l−1 were assessed in one-year-old common carp (Cyprinus carpio L.) exposed for 90 days. Influence on biometric parameters, hematology, biochemistry, histology, and oxidative stress was investigated. Exposure to 0.02, 0.2 and 2.0 μg l−1 showed significant differences oxidative stress biomarkers compared to controls but exposure to 0.2 and 2.0 μg l−1 significantly affected biochemical and hematological profiles. Long-term exposure of terbutryn in carp resulted in slight alterations in internal organs and increased reactive oxygen species formation, resulting in oxidative damage to lipids and proteins and inhibition of antioxidant capacities.

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► Has terbutryn influence to common carp at environmentally realistic concentration.
► Terbutryn increases reactive oxygen species formation in carp.
► Terbutryn causes oxidative damage to lipids and proteins in carp.
► Terbutryn inhibits of antioxidant capacities in carp.
► Terbutryn causes slight alterations in internal organs of carp.