Chiral β-arylalkyl-1H-1,2,4-triazoles as demethylase inhibitors: Biological evaluation and its stereoselective interaction with sterol 14α-demethylase from Penicillium digitatum

► Excellent in vitro antifungal activities against P. digitatum. ► Potential demethylase inhibitors for defense against postharvest pathogens. ► Respective enantiomers showed significantly different inhibitory activities. ► Chiral triazoles present obvious stereoselective interaction with enzyme.