A simple and convenient synthesis of 2-methoxyestradiol from estrone

A simple and straightforward synthesis of 2-methoxyestradiol have been achieved in nine synthetic steps with 21% of overall yield. Being a convenient process, it can be upscaled to industrial process.

A simple and straightforward synthesis of 2-methoxyestradiol has been done with 21% overall yield.Figure optionsDownload as PowerPoint slideHighlights
► Simple synthesis of 2-methoxyestradiol.
► Overall yield = 21%.
► Purity HPLC = 91%.