کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
2028224 1070402 2010 6 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Steroidal saponins and ecdysterone from Asparagus filicinus and their cytotoxic activities
موضوعات مرتبط
علوم زیستی و بیوفناوری بیوشیمی، ژنتیک و زیست شناسی مولکولی زیست شیمی
پیش نمایش صفحه اول مقاله
Steroidal saponins and ecdysterone from Asparagus filicinus and their cytotoxic activities
چکیده انگلیسی

Two new spirostanoides, filiasparosides E (1) and F (2), one new furostanoside, filiasparoside G (3), and one new ecdysterone, stachysterone A-20, 22-acetonide (4), together with six known steroidal saponins, asparagusin A (5), filiasparoside A (6), filiasparoside B (7), aspafilioside A (8), aspafilioside B (9), and filiasparoside C (10) were isolated from the roots of Asparagus filicinus Buch.-Ham. Their structures were elucidated on the basis of spectroscopic and chemical evidence. Compounds 1–10 were investigated for their cytotoxicities against human breast adenocarcinoma MDA-MB-231 cell line and compounds 8–10 exhibited cytotoxic activities with IC50 values ranging from 3.4 to 6.6 μM.

ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Steroids - Volume 75, Issue 10, October 2010, Pages 734–739
نویسندگان
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