Ecdysteroids from Polypodium vulgare L.

Three new compounds (3, 7, and 11) together with eight known phytoecdysteroids (1, 2, 4–6, and 8–10) were isolated from the rhizomes of common polypody, Polypodium vulgare L. The structures of compounds were elucidated by spectroscopic methods including 1D and 2D NMR measurements. The 1H and 13C NMR assignments of compounds 1, 6, 9 and 10 are included.

► The ecdysteroid profile of Polypodium vulgare was investigated.
► Three new natural compounds were isolated, their structure were determinated by MS and NMR analysis.
► Six ecdysteroids previously known from other species were isolated from P. vulgare from the first time.