Genetic and evolutionary perspectives on the interplay between plant immunity and development

There is now ample evidence that plant development, responses to abiotic environments, and immune responses are tightly intertwined in their physiology. Thus optimization of the immune system during evolution will occur in coordination with that of plant development. Two alternative and possibly complementary forces are at play: genetic constraints due to the pleiotropic action of players in both systems, and coevolution, if developmental changes modulate the cost–benefit balance of immunity. A current challenge is to elucidate the ecological forces driving evolution of quantitative variation for defense at molecular level. The analysis of natural co-variation for developmental and immunity traits in Arabidopsis thaliana promises to bring important insights.

► Pleiotropic effects of immunity on development preclude independent evolution.
► Changes in plant development selected by the environment modify the balance between benefits and costs of defense.
► Costs and benefits of immunity can change independently of pathogen populations.