Cell biology of the plant–powdery mildew interaction

Powdery mildew fungi represent a paradigm for obligate biotrophic parasites, which only propagate in long-lasting intimate interactions with living host cells. These highly specialized phytopathogens induce re-organization of host cell architecture and physiology for their own demands. This probably includes the corruption of basal host cellular functions for successful fungal pathogenesis. Recent studies revealed secretory processes by both interaction partners as key incidents of the combat at the plant–fungus interface. The analysis of cellular events during plant–powdery mildew interactions may not only lead to a better understanding of plant pathological features, but may also foster novel discoveries in the area of plant cell biology.

► Plant–powdery mildew interactions are well suited for cell biological analyses.
► Cell-autonomous plant defence responses enable single cell studies.
► MLO proteins are crucial for successful entry of powdery mildews into host cells.
► Secretory processes from both organisms occur at the plant–fungus interface.
► Arabidopsis RPW8 is the first plant protein found at the extrahaustorial membrane.