کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
2046681 1543214 2014 8 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Receptor like proteins associate with SOBIR1-type of adaptors to form bimolecular receptor kinases
موضوعات مرتبط
علوم زیستی و بیوفناوری علوم کشاورزی و بیولوژیک دانش گیاه شناسی
پیش نمایش صفحه اول مقاله
Receptor like proteins associate with SOBIR1-type of adaptors to form bimolecular receptor kinases
چکیده انگلیسی


• Receptor like proteins (RLPs) regulate developmental and defense mechanisms in plants.
• RLPs acting as immunoreceptors form highly diverged receptor families in different plant species.
• The receptor like kinase SOBIR1 acts as a common adaptor for LRR-RLP type immunoreceptors.
• RLPs associate with adaptor kinases to form bimolecular equivalents of receptor kinases.
• Activation of RLP/adaptor complexes requires interaction with a co-receptor.

Receptor like proteins (RLPs) build large protein families in all higher plants. Apart from RLPs with conserved roles in development, an increasing number of RLPs could be associated with functions as immunoreceptors detecting specific patterns from a variety of pathogens. Recent work showed that functionality of these RLPs, at least those with leucine rich repeats in their extracellular domain, depends on association with the common adaptor kinase SOBIR1. We propose that these RLP/adaptor complexes, formed in the absence of ligands, are bimolecular equivalents of genuine receptor kinases. Similar to receptor kinases, activation of these RLP/adaptor complexes seems to require a ligand-dependent interaction step with co-receptors like BAK1 or other SERKs.

ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Current Opinion in Plant Biology - Volume 21, October 2014, Pages 104–111
نویسندگان
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