کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
2046832 | 1073824 | 2011 | 7 صفحه PDF | دانلود رایگان |
Plant disease resistance can be triggered by specific recognition of microbial effectors by plant nucleotide binding-leucine rich repeat (NB-LRR) receptors. Over the last few years, many efforts have greatly improved the understanding of effector and NB-LRR function, but have left a lot of questions as to how effector perception activates NB-LRR induction of defense signaling. This review describes exciting new findings showing similarities and differences in function of diverse plant NB-LRR proteins in terms of pathogen recognition and where and how resistance proteins are activated. Localization studies have shown that some NB-LRRs can activate signaling from the cytosol while others act in the nucleus. Also, the structural determination of two NB-LRR signaling domains demonstrated that receptor oligomerization is fundamental for the activation of resistance signaling.
► Effector-mediated enzymatic activity can be required in both direct and indirect R/Avr recognition systems.
► Some NB-LRRs can activate defense signaling from the cytosolic compartment.
► Crystal structures of two functional NB-LRRs signaling domains have been determined for the first time.
► Receptor oligomerization is a prerequisite for signaling.
Journal: Current Opinion in Plant Biology - Volume 14, Issue 5, October 2011, Pages 512–518