کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
2049678 1074138 2010 6 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Mitochondrial Ca2+ channels: Great unknowns with important functions
موضوعات مرتبط
علوم زیستی و بیوفناوری علوم کشاورزی و بیولوژیک دانش گیاه شناسی
پیش نمایش صفحه اول مقاله
Mitochondrial Ca2+ channels: Great unknowns with important functions
چکیده انگلیسی

Mitochondria process local and global Ca2+ signals. Thereby the spatiotemporal patterns of mitochondrial Ca2+ signals determine whether the metabolism of these organelles is adjusted or cell death is executed. Mitochondrial Ca2+ channels of the inner mitochondrial membrane (IMM) actually implement mitochondrial uptake from cytosolic Ca2+ rises. Despite great efforts in the past, the identity of mitochondrial Ca2+ channels is still elusive. Numerous studies aimed to characterize mitochondrial Ca2+ uniport channels and provided a detailed profile of these great unknowns with important functions. This mini-review revisits previous research on the mechanisms of mitochondrial Ca2+ uptake and aligns them with most recent findings.

ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: FEBS Letters - Volume 584, Issue 10, 17 May 2010, Pages 1942–1947
نویسندگان
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