کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
2050445 | 1074170 | 2008 | 6 صفحه PDF | دانلود رایگان |
![عکس صفحه اول مقاله: cAMP regulates respiration and oxidative stress during rehydration in Anabaena sp. PCC 7120 cAMP regulates respiration and oxidative stress during rehydration in Anabaena sp. PCC 7120](/preview/png/2050445.png)
Cellular cAMP level increased dramatically upon rehydration following dehydration for 24 h in Anabaena sp. PCC 7120, but not in disruptant of an adenylate cyclase gene, cyaC. Oxygen consumption in the cyaC disruptant upon rehydration was higher than that in wild-type strain. Determination of lipid peroxidation and protein carbonylation of the cells revealed greater oxidative stress in the cyaC disruptant than in the wild-type strain during rehydration. Addition of cAMP or KCN to the cyaC disruptant decreased cellular oxygen consumption upon rehydration and oxidative damage. These results suggest that respiration upon rehydration is regulated by cAMP and that the higher respiration activity results in more oxidative damage in cyaC disruptant.
Journal: FEBS Letters - Volume 582, Issue 13, 11 June 2008, Pages 1883–1888