کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
2053097 1074255 2005 4 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Quercetin appears in the lymph of unanesthetized rats as its phase II metabolites after administered into the stomach
موضوعات مرتبط
علوم زیستی و بیوفناوری علوم کشاورزی و بیولوژیک دانش گیاه شناسی
پیش نمایش صفحه اول مقاله
Quercetin appears in the lymph of unanesthetized rats as its phase II metabolites after administered into the stomach
چکیده انگلیسی

Quercetin is a major flavonoid in plant foods and potentially has beneficial effects on disease prevention. The present work demonstrated that quercetin was transported into the lymph after being metabolized in the gastrointestinal mucosa of rats. Glucuronide/sulfate and methylated conjugates of quercetin appeared in the lymph, but not quercetin aglycone. The highest lymphatic concentration was found at as rapid as 30 min after administration, suggesting gastric absorption, whereas the mucosal glucuronidation activity was significantly higher in the duodenum and jejunum than in the stomach. This is the first report to show the lymphatic flavonoid transport pathway from the gastrointestinal tract.

ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: FEBS Letters - Volume 579, Issue 24, 10 October 2005, Pages 5343–5346
نویسندگان
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