کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
2053186 1074264 2005 7 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Identification of the novel evolutionary conserved obstructor multigene family in invertebrates
موضوعات مرتبط
علوم زیستی و بیوفناوری علوم کشاورزی و بیولوژیک دانش گیاه شناسی
پیش نمایش صفحه اول مقاله
Identification of the novel evolutionary conserved obstructor multigene family in invertebrates
چکیده انگلیسی

Insects have evolved chitin-containing structures such as the cuticle or peritrophic membranes that serve to protect their bodies against the hostile environment. The specific mechanisms by which these structures are produced, are mostly unknown. We have identified a novel multigene family, the obstructor family, which encodes ten putatively secreted chitin-binding proteins that are characterized by a stereotype arrangement of a N-terminal signaling peptide and 3 chitin-binding-domains. Gene expression studies in Drosophila melanogaster embryos demonstrate that obstructor family members are expressed in cuticle forming tissues. Using computational and phylogenetic analysis, we show that obstructor genes represent an evolutionary conserved multigene family in invertebrates.

ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: FEBS Letters - Volume 579, Issue 30, 19 December 2005, Pages 6827–6833
نویسندگان
, ,