کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
2062654 | 1076615 | 2013 | 4 صفحه PDF | دانلود رایگان |
عنوان انگلیسی مقاله ISI
Immunohistochemical analysis of steroidogenic acute regulatory protein (StAR) and StAR-binding protein (SBP) expressions in the testes of mice during fetal development
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کلمات کلیدی
موضوعات مرتبط
علوم زیستی و بیوفناوری
علوم کشاورزی و بیولوژیک
علوم دامی و جانورشناسی
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چکیده انگلیسی
SummaryThe expression patterns of steroidogenic acute regulatory protein (StAR) and StAR-binding protein (SBP) in fetal Leydig cells were compared by using immunohistochemistry. While StAR immunoreactivity was detected during the first steps of testis differentiation, SBP expression was detected slightly later. The timing of SBP expression closely correlated with that of the testosterone surge, an event which is known to induce masculinization. Our results suggest that SBP plays an important role in male sexual development via interactions with StAR.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Reproductive Biology - Volume 13, Issue 1, March 2013, Pages 92–95
Journal: Reproductive Biology - Volume 13, Issue 1, March 2013, Pages 92–95
نویسندگان
Katsuhiko Warita, Tomoko Mitsuhashi, Shiho Fukui, Ken-ichi Ohta, Shingo Suzuki, Takanori Miki, Yoshiki Takeuchi, Toshifumi Yokoyama, Hiroshi Kitagawa, Teruo Sugawara, Nobuhiko Hoshi,