کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
2070971 1078713 2016 7 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Carbon nanotubes as vaccine scaffolds
ترجمه فارسی عنوان
نانولوله های کربنی به عنوان داربست واکسن؟
موضوعات مرتبط
علوم زیستی و بیوفناوری بیوشیمی، ژنتیک و زیست شناسی مولکولی بیوتکنولوژی یا زیست‌فناوری
چکیده انگلیسی

Carbon nanotubes display characteristics that are potentially useful in their development as scaffolds for vaccine compositions. These features include stability in vivo, lack of intrinsic immunogenicity, low toxicity, and the ability to be appended with multiple copies of antigens. In addition, the particulate nature of carbon nanotubes and their unusual properties of rapid entry into antigen-presenting cells, such as dendritic cells, make them especially useful as carriers of antigens. Early attempts demonstrating carbon nanotube-based vaccines can be used in both infectious disease settings and cancer are promising.

Depiction of single-wall carbon nanotubes appended with multiple antigens and mixed with an immunological adjuvant, thereby constituting a vaccine.Figure optionsDownload high-quality image (121 K)Download as PowerPoint slide

ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Advanced Drug Delivery Reviews - Volume 65, Issue 15, December 2013, Pages 2016–2022
نویسندگان
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