کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
2071256 1078735 2011 15 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Formation, characterization, and fate of inhaled drug nanoparticles
موضوعات مرتبط
علوم زیستی و بیوفناوری بیوشیمی، ژنتیک و زیست شناسی مولکولی بیوتکنولوژی یا زیست‌فناوری
پیش نمایش صفحه اول مقاله
Formation, characterization, and fate of inhaled drug nanoparticles
چکیده انگلیسی

Nanoparticles bring many benefits to pulmonary drug delivery applications, especially for systemic delivery and drugs with poor solubility. They have recently been explored in pressurized metered dose inhaler, nebulizer, and dry powder inhaler applications, mostly in polymeric forms. This article presents a review of processes that have been used to generate pure (non polymeric) drug nanoparticles, methods for characterizing the particles/formulations, their in-vitro and in-vivo performances, and the fate of inhaled nanoparticles.

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ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Advanced Drug Delivery Reviews - Volume 63, Issue 6, 30 May 2011, Pages 441–455
نویسندگان
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