The silver bullet for cancer prevention: Chemopreventive effects of carotenoids

Cancer has been a leading cause of death in many countries. Chemoprevention of various types of human cancer using dietary nutrients has received a lot of attention and interest in the past decade. Recently, carotenoids have been shown to prevent tumor growth and progression. Carotenoids demonstrated chemopreventive capability by interrupting several stages of cancer including initiation, promotion, progression, and metastasis. The molecular mechanisms of actions are through the modulation of cell-signaling pathways and gene expression. The results of our study suggested that carotenoids could act as chemopreventive agents against the growth and progression of human cancer cells.