کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
2075844 1544971 2015 6 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
miSEA: microRNA set enrichment analysis
موضوعات مرتبط
مهندسی و علوم پایه ریاضیات مدل‌سازی و شبیه سازی
پیش نمایش صفحه اول مقاله
miSEA: microRNA set enrichment analysis
چکیده انگلیسی
We introduce a novel web-based tool, miSEA, for evaluating the enrichment of relevant microRNA sets from microarray and miRNA-Seq experiments on paired samples, e.g. control vs. treatment. In addition to a group of previously annotated microRNA sets embedded in the system, this tool enables users to import new microRNA sets obtained from their own research. miSEA allows users to select from a large variety of microRNA grouping categories, such as family classification, disease association, common regulation, and genome coordinates, based on their requirements. miSEA therefore provides a knowledge-driven representation scheme for microRNA experiments. The usability of this platform was discerned with a cancer type-classification task performed on a set of real microRNA expression profiling experiments. The miSEA web server is available at http://www.baskent.edu.tr/∼hogul/misea
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Biosystems - Volume 134, August 2015, Pages 37-42
نویسندگان
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