کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
2076050 1544987 2014 5 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Probable relationship between partitions of the set of codons and the origin of the genetic code
ترجمه فارسی عنوان
رابطه احتمالی بین پارتیشن های مجموعه ای از کدون ها و مبدأ کد ژنتیکی
کلمات کلیدی
موضوعات مرتبط
مهندسی و علوم پایه ریاضیات مدل‌سازی و شبیه سازی
چکیده انگلیسی

Here we study the distribution of randomly generated partitions of the set of amino acid-coding codons. Some results are an application from a previous work, about the Stirling numbers of the second kind and triplet codes, both to the cases of triplet codes having four stop codons, as in mammalian mitochondrial genetic code, and hypothetical doublet codes.Extending previous results, in this work it is found that the most probable number of blocks of synonymous codons, in a genetic code, is similar to the number of amino acids when there are four stop codons, as well as it could be for a primigenious doublet code. Also it is studied the integer partitions associated to patterns of synonymous codons and it is shown, for the canonical code, that the standard deviation inside an integer partition is one of the most probable.We think that, in some early epoch, the genetic code might have had a maximum of the disorder or entropy, independent of the assignment between codons and amino acids, reaching a state similar to “code freeze” proposed by Francis Crick. In later stages, maybe deterministic rules have reassigned codons to amino acids, forming the natural codes, such as the canonical code, but keeping the numerical features describing the set partitions and the integer partitions, like a “fossil numbers”; both kinds of partitions about the set of amino acid-coding codons.

ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Biosystems - Volume 117, March 2014, Pages 77–81
نویسندگان
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