کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
2076199 1544993 2011 10 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Theoretical approach to modelling and analysis of the bioprocess with product inhibition and impulse effect
موضوعات مرتبط
مهندسی و علوم پایه ریاضیات مدل‌سازی و شبیه سازی
پیش نمایش صفحه اول مقاله
Theoretical approach to modelling and analysis of the bioprocess with product inhibition and impulse effect
چکیده انگلیسی

This work presents the first mathematical model of a bioprocess with product inhibition and impulse effect. To begin with, an exemplary mathematical bioprocess model with product inhibition and impulse effect is formulated. Then, according to the model, the analysis of bioprocess stability is presented. The article expresses the product oscillation period, which provides the precise feeding time frame for the regulator bioprocess to achieve an equivalent stable output as that of a bioprocess with impulse effect in the same production environment. Moreover, in this work, the optimization of the production process with respect to the tunable parameters is investigated, and analytical expressions of their optimal values are provided. Numerical simulations using biological data are presented to illustrate the main results.

ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Biosystems - Volume 104, Issues 2–3, May–June 2011, Pages 77–86
نویسندگان
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