کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
2077265 1079694 2016 15 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Stem and Progenitor Cell-Based Therapy of the Central Nervous System: Hopes, Hype, and Wishful Thinking
ترجمه فارسی عنوان
درمان مبتنی بر سلول های بنیادی و پیش داوری سیستم عصبی مرکزی: امید، هپپپپشن و تفکر آرزو
موضوعات مرتبط
علوم زیستی و بیوفناوری بیوشیمی، ژنتیک و زیست شناسی مولکولی بیوتکنولوژی یا زیست‌فناوری
چکیده انگلیسی

A variety of neurological disorders are attractive targets for stem and progenitor cell-based therapy. Yet many conditions are not, whether by virtue of an inhospitable disease environment, poorly understood pathophysiology, or poor alignment of donor cell capabilities with patient needs. Moreover, some disorders may be medically feasible targets but are not practicable, in light of already available treatments, poor risk-benefit and cost-benefit profiles, or resource limitations. This Perspective seeks to define those neurological conditions most appropriate for cell replacement therapy by considering its potential efficacy and clinical feasibility in those disorders, as well as potential impediments to its application.

ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: - Volume 18, Issue 2, 4 February 2016, Pages 174–188
نویسندگان
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