کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
2078330 1079784 2008 12 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Neural Regeneration and Cell Replacement: A View from the Eye
موضوعات مرتبط
علوم زیستی و بیوفناوری بیوشیمی، ژنتیک و زیست شناسی مولکولی بیوتکنولوژی یا زیست‌فناوری
پیش نمایش صفحه اول مقاله
Neural Regeneration and Cell Replacement: A View from the Eye
چکیده انگلیسی

SummaryNeuronal degenerations in the retina are leading causes of blindness. Like most other areas of the CNS, the neurons of the mammalian retina are not replaced following degeneration. However, in nonmammalian vertebrates, endogenous repair processes restore neurons very efficiently, even after complete loss of the retina. We describe the phenomenon of retinal regeneration in nonmammalian vertebrates and attempts made in recent years to stimulate similar regenerative processes in the mammalian retina. In addition, we review the various strategies employed to replace lost neurons in the retina and the recent use of stem cell technologies to address problems of retinal repair.

ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: - Volume 2, Issue 6, 5 June 2008, Pages 538–549
نویسندگان
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