کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
2081293 1080007 2014 8 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Magnetic nanoparticles: a novel platform for cancer theranostics
ترجمه فارسی عنوان
نانوذرات مغناطیسی: یک پلت فرم جدید برای درمان سرطان است
موضوعات مرتبط
علوم زیستی و بیوفناوری بیوشیمی، ژنتیک و زیست شناسی مولکولی بیوتکنولوژی یا زیست‌فناوری
چکیده انگلیسی


• MNPs act as theranostic agents because of intrinsic magnetic properties.
• MNPs act as a diagnostic tool by acting as contrast agents for MRI.
• MNPs can deliver drugs or genes in a targeted manner by utilizing external magnetic field.
• Magnetic hyperthermia uses MNPs to increase the temperature and kill cancer cells.
• MNPs have reached clinical trials for cancer diagnosis and therapy.

Multifunctional nanoplatforms represent a cutting edge tool in biomedical applications as a result of their applicability in the concurrent monitoring of medical treatment. Magnetic nanoparticles (MNPs) have generated great interest in the field of cancer nanotheranostics owing to their intrinsic magnetic property that enables them to be used as contrast agents in magnetic resonance imaging and as a therapeutic system in conjunction with hyperthermia. In addition, the physical properties and biocompatibility of MNPs help them to act as efficient drug carriers for targeted therapeutic regimes. In this review, we have discussed the different theranostic applications of MNPs. Further, we have raised the current challenges associated with the clinical translation of MNPs along with future opportunities in this field.

The different applications of magnetic nanoparticles that make them suitable as theranostic agents.Figure optionsDownload high-quality image (190 K)Download as PowerPoint slide

ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Drug Discovery Today - Volume 19, Issue 4, April 2014, Pages 474–481
نویسندگان
, ,