کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
2081631 1545190 2007 6 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Unfinished business: target-based drug discovery
موضوعات مرتبط
علوم زیستی و بیوفناوری بیوشیمی، ژنتیک و زیست شناسی مولکولی بیوتکنولوژی یا زیست‌فناوری
پیش نمایش صفحه اول مقاله
Unfinished business: target-based drug discovery
چکیده انگلیسی

The switch in the mid-1980s/early 1990s from a phenotypic approach to a target-based approach to drug discovery has been followed by low productivity of new drugs entering the market. Reasons for the (necessary) switch and unsolved problems with both approaches to drug discovery are discussed. The S-curve theory of new technology development and introduction can act as guide as to when an upturn in productivity can be expected; this should occur during the next decade leading possibly to a new golden age of drug discovery.

ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Drug Discovery Today - Volume 12, Issues 23–24, December 2007, Pages 1007–1012
نویسندگان
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