The epigenomic tool kit

A paradigm shift in nucleic acid sequencing has spurred the development of molecular and computational techniques for the quantitative detection of epigenetic modifications genome-wide. Collectively, these methods provide researchers with an epigenomic 'tool kit' to engage in the molecular characterization of epigenetic states at a scale not imagined only a few years ago. This review provides a description of the current state of the massively parallel sequencing based epigenomic tool kit.