High throughput in vivo phenotyping: The zebrafish as tool for drug discovery for hematopoietic stem cells and cancer

The zebrafish is an important model for the study of development and disease. Its miniature size, large numbers and optical clarity make it advantageous for high-throughput in vivo phenotyping. In this review we will highlight how the zebrafish contributes to drug discovery by in vivo chemical screening and as a disease model.