Innovative mouse models for metastatic disease

Metastasis is a dreaded complication of many malignancies. As a result, the scientific community has been challenged to develop new and innovative approaches to understand the disease progression and to design better therapies. Recently, we developed an approach in which we are able to tract, manipulate and alter metastatic patterns in vivo. These studies lay the groundwork for exploring and developing new therapeutic approaches.

Section editor:Robert M. Mader – Department of Medicine I, Medical University of Vienna, Vienna, Austria