Common characteristics and pathways in neuropathic pain of different etiologies

Neuropathic pain results from diverse patho-physiological reasons. Characteristics of this pain are mainly studied by inducing chronic inflammatory injury of the peripheral nerves in the lower limb. While the etiological differences in neuropathic origin exist at the stage of induction of this pain, some of characteristic features of this pain suggest involvement of central common pathways. Identification of these pathways may assist in discovering novel therapeutic targets for this disease.

Section editor:Min Zhuo – University of Toronto, Toronto, Canada