کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
2082339 | 1080284 | 2006 | 7 صفحه PDF | دانلود رایگان |
عنوان انگلیسی مقاله ISI
Mouse models of asthma and rhinitis to study the role of dendritic cells in sensitization and development of inflammation
دانلود مقاله + سفارش ترجمه
دانلود مقاله ISI انگلیسی
رایگان برای ایرانیان
موضوعات مرتبط
علوم زیستی و بیوفناوری
بیوشیمی، ژنتیک و زیست شناسی مولکولی
بیوتکنولوژی یا زیستفناوری
پیش نمایش صفحه اول مقاله
چکیده انگلیسی
Dendritic cells are held responsible for inducing the primary immune response to inhaled antigen leading to allergic sensitization. Recently, several models have been developed in which various functions of airway dendritic cell subsets such as antigen uptake, migration and T cell stimulatory capacity can be studied in vivo. These models have revealed a crucial role for dendritic cells not only during priming but also during reactivation of Th2 cells in asthma and rhinitis. Dendritic cells are ideal targets for designing novel therapeutics for asthma treatment.
Section editor:Nelly Frossard – Université Louis Pasteur, Strasbourg, France
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Drug Discovery Today: Disease Models - Volume 3, Issue 3, Autumn 2006, Pages 205–211
Journal: Drug Discovery Today: Disease Models - Volume 3, Issue 3, Autumn 2006, Pages 205–211
نویسندگان
Bart N. Lambrecht, Alex Kleinjan,