HIV-derived peptide mimics

Peptides capable of mimicking functionally important regions of HIV proteins are excellent tools to explore structure and function of HIV proteins. Furthermore, such peptides can serve as starting points for novel therapeutic and preventive anti-HIV strategies, including the development of virus entry inhibitors, as well as immunogens to elicit neutralizing antibodies. Recent advances in the design and generation of HIV mimetic peptides are summarized in this article.

Section editor:Peter Timmerman – Pepscan Therapeutics B.V., P.O. Box 2098, 8203 AB Lelystad, The Netherlands